Taking azithromycin with other medicines and herbal supplements (2024)

Cautions with other medicines

There are some medicines that do not mix well with azithromycin.

Tell your doctor if you're taking any of these medicines before you start azithromycin:

  • antacids for indigestion
  • ergotamine or dihydroergotamine – for migraine
  • warfarin, to help prevent blood clots
  • ciclosporin or tacrolimus – medicines to stop your immune system overreacting
  • colchicine, a medicine used for gout and some other inflammatory conditions
  • digoxin for some heart problems
  • rifabutin, an antibiotic
  • nelfinavir, a medicine for HIV
  • a statin medicine to lower your cholesterol, such as simvastatin or atorvastatin

Azithromycin can affect your heartbeat, so it's best not to take it with other medicines that have the same side effect.

Tell your doctor if you're taking medicines that can affect your heartbeat, including:

  • any medicines for an irregular heartbeat (arrhythmia), such as amiodarone or sotalol
  • antidepressants such as citalopram
  • antipsychotics used to treat mental health conditions
  • some anti-sickness medicines, such as dimperidone
  • some antibiotics, such as moxifloxacin

Check the leaflets that come with your medicines and talk to a pharmacist or your doctor if you are worried.

Mixing azithromycin with herbal remedies and supplements

There's not enough information to say that complementary medicines and herbal remedies are safe to take with azithromycin. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.

Important: Medicine safety

Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.

Page last reviewed: 20 January 2022
Next review due: 20 January 2025

Taking azithromycin with other medicines and herbal supplements (2024)

FAQs

What supplements should I not take with azithromycin? ›

Interactions with Azithromycin
  • Alpha-Lipoic Acid.
  • Bromelain.
  • Ethylenediaminetetraacetic Acid (EDTA)
  • Magnesium.
  • Vitamin H (Biotin)
  • Vitamin K. Zinc.

What cannot be mixed with azithromycin? ›

Azithromycin can affect your heartbeat, so it's best not to take it with other medicines that have the same side effect. Tell your doctor if you're taking medicines that can affect your heartbeat, including: any medicines for an irregular heartbeat (arrhythmia), such as amiodarone or sotalol.

What should I avoid after taking azithromycin? ›

In general, any medicine that can increase the risk of bleeding (such as clopidogrel, SSRI antidepressants, or fish oils) may interact with azithromycin. Alcohol may increase the side effects of azithromycin and there is the potential for grapefruit products to interact with azithromycin; however, reports are uncommon.

Can I combine herbal medicine with antibiotics? ›

Herbal remedies such as St John's wort, ginseng and ginkgo biloba could have harmful interactions with conventional drugs, scientists have warned.

What supplements interfere with antibiotics? ›

Antibiotics and mineral supplements: Calcium, magnesium, potassium, iron and other minerals interact with many antibiotics in a way that reduces the level of the antibiotic in the body and makes the treatment ineffective.

Why can't you take magnesium with azithromycin? ›

Your infection may not clear up if you stop using the medicine too soon. If you are taking aluminum or magnesium-containing antacids, do not take them at the same time that you take Zithromax®. These medicines may keep azithromycin from working properly.

What should you not drink with azithromycin? ›

You can eat and drink normally while taking azithromycin. However, if azithromycin makes you feel dizzy do not drink alcohol as it will make you feel worse.

Why is azithromycin no longer recommended? ›

Azithromycin, a commonly prescribed antibiotic for common infections since the early 1990s, is becoming less effective because of growing antimicrobial resistance.

Why do I feel weird after taking azithromycin? ›

This medicine can cause changes in heart rhythms, including QT prolongation. It may change the way your heart beats and cause fainting or serious side effects in some patients.

What herbs should you avoid while taking antibiotics? ›

Herbs that can interfere with medications include black cohosh, curcumin (Curcuma longa), echinacea, garlic (Allium sativum) extract, ginkgo (Ginkgo biloba), American ginseng (Panax quinquefolius), Asian ginseng (Panax quinquefolius), goldenseal (Hydrastis canadensis), green tea (Camellia sinensis) extract, kava kava, ...

Can I take Chinese herbs with antibiotics? ›

Traditional Chinese medicine has a variety of active components, including flavonoids, alkaloids, phenols, and quinones, which can inhibit the growth of drug-resistant bacteria and be used in combination with a variety of antibiotics to treat various drug-resistant bacterial infections.

What herbal supplements should not be taken together? ›

There are several combinations you should definitely avoid: Valerian and Kava: Taking these supplements together can cause dizziness, confusion, drowsiness, respiratory depression, impaired judgment, and motor control, and difficulty in concentrating. 2. , "Drug Interactions between Kava and Valerian Root", Drugs.com.

Can you take vitamin D with azithromycin? ›

Interactions between your drugs

No interactions were found between azithromycin and Vitamin D3.

Does vitamin C interact with azithromycin? ›

Interactions between your drugs

No interactions were found between azithromycin and Vitamin C.

Can you take omega-3 with azithromycin? ›

No interactions were found between azithromycin and Fish Oil. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

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